SEX STEROID BINDING PROTEIN (SBP) IN PREMATURE INFANTS
نویسندگان
چکیده
منابع مشابه
Identification of a novel sex steroid binding protein.
We describe a cytoplasmic steroid binding protein in the chick oviduct which has intriguing characteristics. This protein binds [3H]estradiol with high affinity (Kd = 30 X 10(-9) M) and limited capacity (300 fmol/mg of cytosol protein). It sediments at 8 S in low-salt sucrose density gradients and at 4 S in high-salt gradients. Unlike the estrogen receptor, however, this protein also binds prog...
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The sex steroid-binding protein of human plasma SBP (or sex hormone-binding globulin, SHBG) was specifically inhibited with the alkylating affinity label, 17 beta-[[( 2-14C]bromoacetyl)oxy]-5 alpha-androstan-3-one. The natural ligand, 5 alpha-dihydrotestosterone, was shown to protect against inactivation and labeling. The steroid-binding activity of the protein was abolished when approximately ...
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The normal pregnant woman and the newborn infant both have raised hormonal iodine levels (Rose, Russell, and Starr, 1963; Pickering et al., 1958). The very early fetus has a low hormonal iodine which rises as gestation proceeds, but the level in premature babies is still lower than that of full-term infants (Andreoli and Robbins, 1962; Rose et al., 1963; Marks and Man, 1965). The serum protein-...
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It has been shown that some of the mycotic infections especially systemic mycoses show increased male susceptibility and some steroids have been known to influence the immune response. Researchers found that some fungi including yeasts use "message molecules" including hormones to elicit certain responses, especially in the sexual cycle, but until recently no evidence was available to...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1988
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198801000-00050